Topical Antibacterial
Introduction Although many antibacterial drugs are available in topical preparations , some are potentially hazardous and frequently, their use is not necessary if adequate hygienic measures can be taken . Moreover, not all skin conditions that are oozing, crusted or characterized by pustules are actually infected. Topical Options Aminoglycosides (e.g. neomycin, gentamicin) Neomycin sulphate may cause sensitization and there is cross-sensitivity with other aminoglycosides such as gentamicin. If large areas of skin are being treated, ototoxicity may also be a hazard with aminoglycoside antibiotics, particularly in children, in the elderly and in those with renal impairment. Clindamycin For acne vulgaris . Fusidic acid A narrow-spectrum antibacterial used for staphylococcal infections . Metronidazole Is used topically for rosacea and to reduce the odour associated with anaerobic infections . Mupirocin Is effective for skin infections (including mild impetigo) , particularly those due to...