Gestational Diabetes Mellitus

Introduction Historically, the term "gestational diabetes mellitus (GDM)" has been defined as onset or first recognition of abnormal glucose tolerance during pregnancy. Women with type 1 or 2 diabetes diagnosed prior to pregnancy are classified as having pre-existing diabetes. NICE guidelines recommend that women with pre-existing diabetes who plan for pregnancy to aim for HbA1c <6.5% (48 mmol/mol) if this is achievable without causing hypoglycaemia . Any reduction in HbA1c level towards the target is likely to reduce the risk of congenital malformations in the baby. Those with HbA1c >10% (86 mmol/mol) are strongly advised not to get pregnant because of the associated risks. NOTE: Low-dose aspirin is recommended for preeclampsia prevention in both pre-existing type 1 and 2 diabetes. Complications of GDM Complications of pregnancy which is more common in GDM include: Large for gestational age (LGA) infant and macrosomia Preeclampsia and gestational hypertension ...